Elaheh Talebi-Garakani; Sajad Aslani; Rozita Fathi; Alii Reza Safarzadeh; Fatemeh Roudbari
Volume 4, Issue 1 , May 2014, , Pages 15-26
Abstract
Aim: Omentin-1 is an adipokine that is highly secreted in visceral adipose tissue compared to subcutaneous adipose tissue and increases insulin sensitivity. The aim of the present study was to investigate the effect of 8-week resistance training on omentin-1¬ plasma levels in insulin resistant male ...
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Aim: Omentin-1 is an adipokine that is highly secreted in visceral adipose tissue compared to subcutaneous adipose tissue and increases insulin sensitivity. The aim of the present study was to investigate the effect of 8-week resistance training on omentin-1¬ plasma levels in insulin resistant male rats. Method: Twenty-four Wistar male rats¬ with average weight¬ 161±23 gr were randomly divided into three groups: health control, insulin resistance control, insulin resistance training. After fructose-inducing insulin resistance to the two groups of insulin resistance control and insulin resistance training bleeding in all subjects was done then training group was exercised for 8 weeks (3d/wk). In the training protocol, a ladder was used on which rats carriedpen loads suspended from their tails. After the training session omentin-1, insulin, glucose, lipids profile plasma concentration and (HOMA-IR) index were measured. Results: The results of this study indicate that 8 weeks of resistance training can cause significant increase of omentin-1 and HDL-C plasma concentration in insulin resistance training group (P≤0.05) and insulin, glucose, cholesterol, LDL-C, TG plasma concentration and (HOMA-IR) index were decreased. Conclusion: This study indicates that resistance training increases omentin-1 plasma concentration in insulin resistance rats and improves lipids and metabolic profile.
Ali Reza Safarzade; Fahimeh Shafiee; Elaheh Talebi-Garakani; Rozita Fathi
Volume 4, Issue 1 , May 2014, , Pages 27-38
Abstract
Aim: The purpose of this study was to investigate the effects of aerobic exercise training on plasma vaspin concentration and insulin resistance index in sedentary overweight women. Methods: Twenty six sedentary overweight women (aged: 43.1 ± 12.6 year, weight: 73.4 ± 10.0 kg, BMI: 29.1 ...
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Aim: The purpose of this study was to investigate the effects of aerobic exercise training on plasma vaspin concentration and insulin resistance index in sedentary overweight women. Methods: Twenty six sedentary overweight women (aged: 43.1 ± 12.6 year, weight: 73.4 ± 10.0 kg, BMI: 29.1 ± 3.2 kg/m2) voluntarily participated in an 8-weeks aerobic exercise training program included running with 40- 80% reserve heart rate, 20- 45 min/day. Anthropometric and metabolic parameters in addition to plasma vaspin concentration were measured at baseline and after 8 weeks of the training program. To compare changes in variables according to body composition alterations, we divided the subjects into responders (defined as participants who lost ≥1% of baseline body fat percentage), and non-responders (defined as participants with no change or <1% reduction in body fat percentage). Results: After 8 weeks of aerobic exercise training we did not find any significant changes in plasma vaspin concentration. Nevertheless, body weight and body fat percentage decreased significantly (P≤0.05) and plasma vaspin concentrations increased significantly (P≤0.05) in responders, but not in non-responders. Changes in plasma vaspin concentrations were significantly correlated with changes in plasma insulin and glucose levels, and insulin resistance index (HOMA-IR) only in non-responders. Conclusions: This study indicated that reduction in body fat percentage induced by aerobic exercise training could be an effective factor to increase plasma vaspin levels in sedentary overweight women.
Elaheh Talebi-Garakani; Rozita Fathi; Alireza Safarzade; Hamideh Moradi; Rihaneh Delbari
Volume 2, Issue 2 , July 2012, , Pages 91-100
Abstract
Abstract
Aim: The purpose of this study was to investigate the effect of 4 week resistance training on plasma omentin-1 levels in Streptozotocin induced diabetic rats.
Method: In this experimental study 24 male Wistar rats with mean weight of 288±22g (mean±SD) were randomly divided into 3 groups: ...
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Abstract
Aim: The purpose of this study was to investigate the effect of 4 week resistance training on plasma omentin-1 levels in Streptozotocin induced diabetic rats.
Method: In this experimental study 24 male Wistar rats with mean weight of 288±22g (mean±SD) were randomly divided into 3 groups: non-diabetic control (n=8), diabetic control (n=8), and diabetic training (n=8). Diabetes was induced by a single intra-peritoneal injection of streptozotocin (STZ) at a dose of 55 mg/kg. The resistance training consisted of climbing a ladder carrying a load suspended from the tail (3 days/wk, for 4 wk). After 4-week body weight, plasma omentin-1, glucose, insulin, non-esterified fatty acids (NEFA) concentrations and lipid profiles were measured.
Results: After four weeks plasma omentin-1 levels in trained diabetic rats was higher when compared with diabetic control group, but it was not statistically significant. We did not find any significant difference in plasma glucose, insulin, NEFA and lipid profile levels between all groups. Body weights alteration in diabetic resistance trained rats were significantly lower compared with the diabetic control group.
Conclusion: The results of this study indicated that plasma levels of glucose, insulin, lipid profile and omentin-1 remained unchanged in diabetic rats due to 4 weeks resistance training. Short duration of training program appears to be an effective factor in the absence of significant changes in plasma omentin-1 levels.
Key words: Omentin-1, Resistance training, Diabetes
